91影库Deuel Conference on Lipids
Jan. 21–24, 2025
Hyatt Regency, Long Beach, Calif.
The 91影库Deuel conference is a must-attend event for leading lipids investigators — and for scientists who’ve just begun to explore the role of lipids in their research programs. This event will bring together a diverse array of people including those who have not attended Deuel or perhaps any lipid meeting before.
The conference is a forum for the presentation of new and unpublished data, and attendees enjoy the informal atmosphere that encourages free and open discussion. Interested scientists are invited to attend and encourage trainees to submit abstracts.
If you have any questions, contact meetings@asbmb.org.
Organizers
University of North Carolina at Chapel Hill
University of Texas Southwestern Medical Center
Sign up for email updates about this conference
Sponsors
Program schedule
Tuesday January 21
Wednesday January 22
Thursday January 23
Friday January 24
Tuesday agenda
Badge pickup
Dinner on own
Opening reception
Opening remarks
Sarah Cohen & Philipp Scherer
The Richard J. Havel Lecture
Mechanisms for lipotoxicity in cardiometabolic disease
Dale Abel, University of California, Los Angeles
Wednesday agenda
Breakfast
Session I 鈥� Heart
Chair: Silvia Corvera
Investigating protein lipidation in cardiac development and disease
Whitney Edwards, University of North Carolina
Cardiomyocyte ceramides drive diastolic dysfunction
Will Holland, University of Utah
TAFAZZIN deficiency perturbs mitochondrial development during cardiomyocyte maturation
Short talk
Short talk
Nanami Senoo, Johns Hopkins University
Altered sphingolipid biosynthetic flux and lipoprotein trafficking contribute to trans fat-induced atherosclerosis
Short talk
Short talk
Christian Metallo, Salk Institute for Biological Studies
Coffee break
Session I 鈥� Heart (cont.)
Chair: Silvia Corvera
Targeting cardiac fatty acid oxidation as an approach to treat heart failure
Gary Lopaschuk, University of Alberta
Unlocking the world without serious chronic diseases through innovation
James Mu, Novo Nordisk
Tools to study membrane contact sites and lipid trafficking between lipid droplets and metabolic organelles
Short talk
Short talk
Gregory Miner, University of North Carolina
A new frontier in disease biomarkers and therapeutic targets
Short talk
Short talk
Jyothi Nagajyothi, Hackensack Meridian Health
Free time
Lunch on own
Poster session reception
Dinner
Session II 鈥� GI tract
Chair: Rodney Infante
Shedding light on the dark-yolk phenotype: Identifying novel regulators of lipid metabolism using forward genetic and small molecule screens in zebrafish
Steven Farber, Johns Hopkins University
The role of lipogenesis in MASLD
Jay Horton, University of Texas Southwestern Medical Center
How lipid ingestion is sensed by the intestine
Frank Reimann, University of Cambridge
Global approach to characterizing liver lipid changes in mice treated with GIP-RA, GLP-1RA, long-acting glucagon (IUB288), and a combined triple-agonist (GGG)
Short talk
Short talk
Mackenzie Pearson, Eli Lilly and Company
Identification of MARCH6 as SREBP1 E3 ligase to inhibit lipid accumulation in cells and mouse liver
Short talk
Short talk
Shimeng Xu, University of Texas Southwestern Medical Center
Thursday agenda
Breakfast
Session III 鈥� Kidney
Chair: Becky Haeusler
The multifaceted role of kidney tubule mitochondrial dysfunction in kidney disease development
Katalin Susztak, University of Pennsylvania
Role of sphingolipids in obesity, diabetes, and age-related kidney disease
Moshe Levi, Georgetown University Medical Center
Coffee break
Session III 鈥� Kidney (cont.)
Chair: Becky Haeusler
Podocyte lipid droplets in glomerular diseases
Alessia Fornoni, University of Miami
Proximal tubule lipotoxicity in diabetic kidney disease
Jeff Schelling, Case Western Reserve University
Mouse ischemic injury generates unique renal lipid droplets with increased arachidonic acid metabolism
Short talk
Short talk
Chetana Jadhav, University of Texas Southwestern Medical Center
Fatty acid oxidation in injured kidney tubules: a role for the peroxisome?
Short talk
Short talk
Leslie Gewin, Washington University in St. Louis
Free time
Lunch on own
Poster session reception
Dinner
Session IV 鈥� Brain
Chair: Sarah Cohen
ApoE receptors and the origin of Alzheimer's disease
Joachim Herz, University of Texas Southwestern Medical Center
An allelic series of lipidated ApoE drives neuronal lipofuscinosis
Gil Di Paolo, Denali Therapeutics Inc.
Glucosylceramide-induced α-synuclein transmission in Parkinson's disease
Maria Ioannou, University of Alberta
Trimming brain fat with sleep
Amita Sehgal, University of Pennsylvania
PLA2G15 is a lysosomal BMP hydrolase and its targeting ameliorates lysosomal disease
Short talk
Short talk
Kwamina Nyame, Stanford University
Nuclear envelope associated lipid droplets are enriched in cholesteryl esters and increase during inflammatory signaling
Short talk
Short talk
Lauri Vanharanta, University of Helsinki
Friday agenda
Breakfast
Session V 鈥� Liver and adipose
Chair: Philipp Scherer
Spatially resolved rewiring of mitochondria-lipid droplet interactions in hepatic lipid homeostasis
Natalie Porat鈥揝hliom, National Cancer Institute
A genome-wide CRISPR screen identifies INPP1 as a novel RXR target gene and links inositol phosphate metabolism to hepatic lipid deposition
Short talk
Short talk
Magdalene Montgomery, University of Melbourne
SPRINGing off the lock: how SPRING licenses SREBP activity
Short talk
Daniel Kober, University of Texas Southwestern Medical Center
Short talk
Daniel Kober, University of Texas Southwestern Medical Center
Noam Zelcer, University of Amsterdam
CLCC1, a central node in the metabolism and transport homeostasis (MATH) of bulk lipids
Xiao-Wei Chen, Peking University
Poster prize announcements,
Coffee break
Session V 鈥� Liver and adipose (cont.)
Chair: Philipp Scherer
Human thermogenic adipose tissue development and therapeutic potential
Silvia Corvera, University of Massachusetts
Importance of alterations in adipose tissue biology in the metabolic benefit of weight loss
Samuel Klein, Washington University in St. Louis
Lean adipocytes suppress breast cancer by secreting the oxylipin 9(S)-HODE and triggering ferroptosis
Short talk
Short talk
Keren Hilgendorf, University of Utah
Distinct adipose tissue fibrosis and transcriptomic profiles in people with HIV: links to insulin resistance beyond adiposity
Short talk
Short talk
Diana Alba, University of California, San Francisco
Additional resources
Sponsorships
Opportunities for companies that have a general interest in the areas of lipid metabolism, atherosclerosis, obesity, diabetes and Alzheimer's disease.