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O-GlcNAcylation in health and disease

July 10–13, 2025
JB Duke Hotel, Durham, N.C.

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• Register

2024 marked the 40th anniversary of the discovery of protein O-GlcNAcylation. Since its discovery, the importance of post-translational protein O-GlcNAcylation has been recognized across diverse biomedical research areas. It plays a pivotal role in helping us understand how environmental factors impact signaling pathways and the onset of a range of diseases. This modification of proteins found in the nucleus, mitochondria and cytoplasm has far-reaching implications for governing cellular biology, including epigenetics, cell cycle regulation, proteostasis and more. Additionally, disruptions in O-GlcNAcylation are associated with cardiovascular disease, diabetes, neurological disorders and various forms of cancer.

Despite 40 years of research and over 15,000 substrates described to date, O-GlcNAcylation remains incompletely understood. Recent breakthroughs in identifying the specific functions of proteins and their connections to many diseases have positioned it as an emerging field with important implications for physiology and disease.

This meeting will draw experts from around the world to discuss the O-GlcNAc cycling enzymes and the O-GlcNAc modification in modulating protein function in basic biological processes as well as in disease states, including diabetes, cancer, cardiovascular disease and neurological diseases. Additionally, graduate and postdoctoral students will be selected for oral talks and have opportunities to discuss their work at poster sessions.

If you want to learn about O-GlcNAc, have just started working on this modification, want to find a collaborator for your next project, or learn the latest discovery in the field, this meeting is for you!

Important dates

Speakers

• Emilyn Alejandro, University of Minnesota
• John Hanover, National Institutes of Health
• Olof Lagerlöf,&²Ô²ú²õ±è;±«³¾±ðÃ¥ University
• Tony Lefebvre, University of Lille  
• Billy Wai-Lung Ng, Chinese University of Hong Kong
• Gulcin Pekkurnaz, University of California, San Diego
• Tai-ping Sun, Duke University
• Daan Van Aalten, Aarhus University
• Lance Wells, University of Georgia
• Melissa Westwood, University of Manchester
• Xiaoyong Yang, Yale University

Registration

91Ó°¿âmembers will receive a $50 discount on their registration fee which will be applied during checkout. Not a member? Join ASBMB and save!

NOTE: Registration is on a first come, first served basis and will remain open until capacity is reached. This may mean that the conference registration closes before the officially posted registration deadline. To secure your spot at the conference, we encourage you to register early.

What’s included

• All sessions, poster sessions and meeting materials for the O-GlcNAcylation in health and disease conference.
• Lodging for 3 nights (arriving on July 10, departing on July 13) at the .
  • Lodging can be single or double occupancy.
• The following meals are included in your registration fee:
  • Daily refreshment breaks
  • Breakfast on July 11, 12 & 13
  • Lunch on July 11 & 12

Note: Lodging is not included in the commuter rates.

Registration changes

Registration changes will be accepted as space allows until June 6, 2025, and can be made by contacting meetings@asbmb.org.

Cancellation policy

Cancellations received in writing on or before June 6, 2025, are subject to a $100 processing fee. No refunds will be issued for cancellations after June 6 due to final guarantee commitments. Email meetings@asbmb.org and attach a copy of your meeting registration receipt/paid invoice to cancel your registration.

Location

The conference will be held at the JB Duke Hotel, 230 Science Drive, Durham, NC 27708.

Visas

All individuals traveling from outside of the United States should apply for a visa as soon as possible and at least four to five months prior to their date of travel.

• The most up-to-date information about traveling to the U.S. can be found at the .
• Scientists visiting the U.S. may find helpful information at the .
• .

Please do not wait until you receive your registration confirmation before applying for a visa. We encourage you to apply for your visa right away if you are considering attending to avoid delays and longer than anticipated wait times.

If you need a letter of invitation for your visa process, please email meetings@asbmb.org.

• Please include ‘LETTER OF INVITATION’ as the subject line of this email.
• Body of email must include:
  • Your name as it appears on your passport
  • Your affiliation and mailing address
  • Best contact number and email address

Health and safety

Mask-wearing and other health and safety measures will be determined based on local, state and venue guidelines and will be communicated to attendees prior to the conference.