Ferroptosis: Crosstalk between metabolism and biochemical homeostasis
April 13–15, 2025
Chicago

Ferroptosis is form of cell death that integrates biochemistry and molecular biology related to iron homeostasis, redox biology and diverse aspects of metabolism. Ferroptosis was first reported in the Stockwell lab in 2012, and the field has rapidly grown since then, with more than 10,000 papers on ferroptosis currently in PubMed. This meeting will focus on the biochemical and molecular aspects of ferroptosis and how they relate to normal homeostasis and disruptions of homeostasis. Recent exciting advances in new pathways controlling ferroptosis make a meeting on this topic timely.
Attendees will learn about this emerging area of ferroptosis and how it intersects with biochemistry, molecular biology, cell homeostasis and numerous related fields, such as iron, metabolism and ROS biology. In addition, attendees will meet experts in this set of fields, be able to present their relevant research, get new ideas and form new collaborations in this rapidly growing field.
Organizers



Sponsors
Speakers
Aberrant mitochondrial metabolism in Alzheimer’s disease links energy stress to ferroptosis
Scott Ayton, University of Melbourne
Studying and targeting ferroptosis in cancer
Gan Boyi, MD Anderson Cancer Center
Truncated oxidized phospholipids mediate synchronized ferroptosis and contribute to acute kidney injury
Quan Chen, Nankai University
Sculpturing embryos via ferroptotic trigger waves
Sheng-hong Chen, Institute of Molecular Biology Academia Sinica
Ferroptosis regulation by lipid metabolism
Scott Dixon, Stanford University
Understanding the complexity of p53-mediated ferroptosis in tumor suppression
Wei Gu, Columbia University
Targeting metabolism in glioblastoma
Dominique Higgins, University of North Carolina at Chapel Hill
Phospholipid remodeling in ferroptosis and cancer treatment
Xuejun Jiang, Memorial Sloan Kettering Cancer Center
Defensive cell death in plants: Regulating ferroptosis against pathogen invasion
Namsoo Jwa, Sejong University
Selenium’s paradox in the regulation of ferroptosis
Namgyu Lee, Dankook University
Targeting ferroptosis for TNBC therapy
Sima Lev, Weizmann Institute of Science
Iron metabolism in adipocytes – All roads lead to ferroptosis
Philip Scherrer, University of Texas Southwestern Medical Center
Ferroptosis and male infertility: Exploring new therapeutic avenues in reproductive health
Cui Shaojie, Huazhong Agricultural University
The role of selenium deficiency and selenocysteine lyase in ferroptotic cell death
Brianna Shimada, University of Hawaii
Diet, drugs and disease: Ferroptosis as a new therapeutic paradigm
Brent Stockwell, Columbia University
Mechanisms of immunomodulation during ferroptosis
Peter Vandenabeele, VIB
Ferroptosis: The driver for alcoholic liver disease
Jin Ye, University of Texas Southwestern Medical Center
Dissecting NRF2's multifaceted control points in ferroptosis defense
Donna Zhang, Scripps Research Institute
Program schedule
Sunday, April 13 | |
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7–9 p.m. | Welcome & Session 1 |
9–10 p.m. | Reception |
Monday, April 14 | |
9 a.m. – 12 p.m. | Session 2 |
12–2 p.m. | Lunch |
2–5 p.m. | Session 3 |
5–7 p.m. | Poster session |
Tuesday, April 15 | |
9 a.m. – 12 p.m. | Session 4 |
12–1 p.m. | Lunch |
1–4 p.m. | Session 5 |
4 p.m. | Adjourn |
7:30–9:30 p.m. | Annual meeting closing reception |