Metabolism

Scientists find unexpected correlation between age and HDL-C levels
In a 30-year multicenter study, researchers determined what factors predict HDL-C concentration. In their analysis, they found that HDL-C levels grew with increasing age and physical activity.

Butter, olive oil, coconut oil — what to choose?
Depending on the chain length and origin of the fat, regular fat consumption changes the specific makeup of fats in bloodstream and affect mild to severe cholesterol patterns. Read about this recent Journal of Lipid Research study.

Meet Shannon Reilly
The JLR junior associate editor discusses the role of adipocytes in obesity at Weill Cornell Medical School.

Elusive zebrafish enzyme in lipid secretion
Scientists discover that triacylglycerol synthesis enzyme drives lipoproteins secretion rather than lipid droplet storage. Read more about this recent study from the Journal of Biological Chemistry.

New tool matches microbial and metabolic metaproteomic data
Scientists develop a bioinformatics program that maps omics data to metabolic pathways. Read about this recent article published in Molecular & Cellular Proteomics

How transcription factor mutations shape diabetes risk
Scientists identify structural differences between the transcription factors that control insulin regulation, shedding light on their roles in diabetes. Read more about this recent study from the Journal of Biological Chemistry.

Fat cells are a culprit in osteoporosis
Scientists reveal that lipid transfer from bone marrow adipocytes to osteoblasts impairs bone formation by downregulating osteogenic proteins and inducing ferroptosis. Read more about this recent study from the Journal of Lipid Research.

Exploring lipid metabolism: A journey through time and innovation
Recent lipid metabolism research has unveiled critical insights into lipid–protein interactions, offering potential therapeutic targets for metabolic and neurodegenerative diseases. Check out the latest in lipid science at the 91Ó°¿âannual meeting.

91Ó°¿ânames 2025 JBC/Tabor Award winners
The six awardees are first authors of outstanding papers published in 2024 in the Journal of Biological Chemistry.