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Are you tired of binging reruns on Netflix?  Maybe you need a break from reality TV but you’re not sure where to turn for high-quality entertainment?  Look no further — the nucleus has it all.  There’s mystery, murder, machines of extraordinary complexity and visually stunning landscapes. 

Stories in nuclear signaling are unraveling at an unprecedented pace thanks to technological and conceptual advances in chemistry, biochemistry and cell biology. Our speakers will address long-standing questions about organism development, cellular identity and the genetic basis for disease. 

You will hear about how cutting-edge interdisciplinary approaches are being used to uncover new regulatory mechanisms underlying transcription, genome structure, and other phenomena in the nucleus. We will also discuss how rapid progress in the field is inspiring new therapeutic approaches for diseases related to dysfunctional nuclear processes.

You don’t want to miss this — even the cytosol junkies will be on the edge of their seats.

Keywords:  Enzyme mechanism, genetics and disease, chemical probes, transcription regulation, chromatin modifications, genome structure.

Who should attend: You. Our speakers span a wide breadth of biological phenomena, scientific disciplines and technologies. We have something for everyone. Current projections: standing room only.

Your session’s theme song:  by John Williams

This song is about the most important genetics experiment ever performed.

This session is powered by “hot, nasty, bad-*ss speed.” — Eleanor Roosevelt, Talladega Nights

Signaling mechanisms in the nucleus

Chemical strategies to study nuclear processes

Chair: Aaron Johnson

Anna Mapp, University of Michigan

Glen Liszczak, University of Texas Southwestern Medical Center

Oliver Bell, University of Southern California Kerk School of Medicine

Minkui Luo, Memorial Sloan Kettering Cancer Center

Chromatin organization, replication and repair

Chair: Katharine Diehl

Aaron Streets, University of California, Berkeley

Aaron Johnson, University of Colorado Anschutz Medical Campus

Carl Wu, Johns Hopkins University

Serena Sanulli, Stanford University

Chromatin modifications in the nucleus

Chair: Glen Liszczak

Alex Ruthenberg, University of Chicago

Katharine Diehl, University of Utah

Tim Stasevich, Colorado State University

Phil Cole, Harvard University